Bosses
General unique pool
Uniques that are not tied to one boss, and where else uniques come from.
How it works
Most uniques are not tied to a boss. They can drop from anything that drops uniques: enemies in the open world, Helltide chests, dungeons, the Pit, and the general half of a lair boss's hoard.
A lair boss's first unique always comes from its own pool. After that, each unique has an even chance of coming from the boss's pool or from this one. See Lair bosses for the full rules.
The general pool
42 uniques, sorted by class. It leaves out every item that a boss page lists in its own pool.
Also linked to a boss
These items are tied to a boss as well as dropping more widely, so they are kept apart from the main list.
Runewords
Not random drops. Each is made in the Horadric Cube from a Common base item and the runes below. See Runes and Runewords for how it works.
Special items
Uniques whose source is not confirmed yet. Most are novelty items tied to events or hidden encounters.